Asymmetric predominantly ipsilateral blepharospasm and contralateral parkinsonism in an elderly patient with a right mesencephalic cyst
Identifieur interne : 005066 ( Main/Exploration ); précédent : 005065; suivant : 005067Asymmetric predominantly ipsilateral blepharospasm and contralateral parkinsonism in an elderly patient with a right mesencephalic cyst
Auteurs : Singer ; Norman J. Schatz ; Brian Bowen ; David Eidelberg [États-Unis] ; Ken Kazumata [États-Unis] ; Linda Sternau [États-Unis] ; Lisa M. Shulman ; William J. WeinerSource :
- Movement Disorders [ 0885-3185 ] ; 1998-01.
English descriptors
- KwdEn :
- Aged, Arachnoid Cysts (complications), Arachnoid Cysts (pathology), Arachnoid Cysts (physiopathology), Arm, Blepharospasm, Blepharospasm (etiology), Blepharospasm (pathology), Blepharospasm (physiopathology), Dystonia, Female, Humans, Magnetic Resonance Imaging, Mesencephalon (pathology), Mesencephalon (physiopathology), Midbrain cyst, Parkinson Disease (etiology), Parkinson Disease (pathology), Parkinson Disease (physiopathology), Parkinsonism, Tomography, Emission-Computed.
- MESH :
- complications : Arachnoid Cysts.
- etiology : Blepharospasm, Parkinson Disease.
- pathology : Arachnoid Cysts, Blepharospasm, Mesencephalon, Parkinson Disease.
- physiopathology : Arachnoid Cysts, Blepharospasm, Mesencephalon, Parkinson Disease.
- Aged, Arm, Female, Humans, Magnetic Resonance Imaging, Tomography, Emission-Computed.
Abstract
A 66‐year‐old woman presented with a 3‐year history of predominantly right‐sided blepharospasm and a 1‐year history of progressive predominantly left‐sided hemiparkinsonism manifested by a left upper extremity resting tremor and left‐sided bradykinesia. Magnetic resonance imaging of the brain revealed a large right mesencephalic cyst with mass effect. Positron emission tomography revealed bilateral striatal hypometabolism consistent with nigrostriatal dopaminergic dysfunction. The association of predominantly ipsilateral blepharospasm and predominantly contralateral hemiparkinsonism is very rare, and its association with a posterior fossa space‐occupying lesion has been reported only once. This is the second report of such an association and the first description of adult‐onset symptomatology.
Url:
DOI: 10.1002/mds.870130125
Affiliations:
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<term>Arachnoid Cysts (physiopathology)</term>
<term>Arm</term>
<term>Blepharospasm</term>
<term>Blepharospasm (etiology)</term>
<term>Blepharospasm (pathology)</term>
<term>Blepharospasm (physiopathology)</term>
<term>Dystonia</term>
<term>Female</term>
<term>Humans</term>
<term>Magnetic Resonance Imaging</term>
<term>Mesencephalon (pathology)</term>
<term>Mesencephalon (physiopathology)</term>
<term>Midbrain cyst</term>
<term>Parkinson Disease (etiology)</term>
<term>Parkinson Disease (pathology)</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Parkinsonism</term>
<term>Tomography, Emission-Computed</term>
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<term>Parkinson Disease</term>
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<term>Blepharospasm</term>
<term>Mesencephalon</term>
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<front><div type="abstract" xml:lang="en">A 66‐year‐old woman presented with a 3‐year history of predominantly right‐sided blepharospasm and a 1‐year history of progressive predominantly left‐sided hemiparkinsonism manifested by a left upper extremity resting tremor and left‐sided bradykinesia. Magnetic resonance imaging of the brain revealed a large right mesencephalic cyst with mass effect. Positron emission tomography revealed bilateral striatal hypometabolism consistent with nigrostriatal dopaminergic dysfunction. The association of predominantly ipsilateral blepharospasm and predominantly contralateral hemiparkinsonism is very rare, and its association with a posterior fossa space‐occupying lesion has been reported only once. This is the second report of such an association and the first description of adult‐onset symptomatology.</div>
</front>
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