Movement Disorders (revue)

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Asymmetric predominantly ipsilateral blepharospasm and contralateral parkinsonism in an elderly patient with a right mesencephalic cyst

Identifieur interne : 005066 ( Main/Exploration ); précédent : 005065; suivant : 005067

Asymmetric predominantly ipsilateral blepharospasm and contralateral parkinsonism in an elderly patient with a right mesencephalic cyst

Auteurs : Singer ; Norman J. Schatz ; Brian Bowen ; David Eidelberg [États-Unis] ; Ken Kazumata [États-Unis] ; Linda Sternau [États-Unis] ; Lisa M. Shulman ; William J. Weiner

Source :

RBID : ISTEX:BBF5FCD8B447B0997C5DFD4BBC3B301553E240F5

English descriptors

Abstract

A 66‐year‐old woman presented with a 3‐year history of predominantly right‐sided blepharospasm and a 1‐year history of progressive predominantly left‐sided hemiparkinsonism manifested by a left upper extremity resting tremor and left‐sided bradykinesia. Magnetic resonance imaging of the brain revealed a large right mesencephalic cyst with mass effect. Positron emission tomography revealed bilateral striatal hypometabolism consistent with nigrostriatal dopaminergic dysfunction. The association of predominantly ipsilateral blepharospasm and predominantly contralateral hemiparkinsonism is very rare, and its association with a posterior fossa space‐occupying lesion has been reported only once. This is the second report of such an association and the first description of adult‐onset symptomatology.

Url:
DOI: 10.1002/mds.870130125


Affiliations:


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Le document en format XML

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<div type="abstract" xml:lang="en">A 66‐year‐old woman presented with a 3‐year history of predominantly right‐sided blepharospasm and a 1‐year history of progressive predominantly left‐sided hemiparkinsonism manifested by a left upper extremity resting tremor and left‐sided bradykinesia. Magnetic resonance imaging of the brain revealed a large right mesencephalic cyst with mass effect. Positron emission tomography revealed bilateral striatal hypometabolism consistent with nigrostriatal dopaminergic dysfunction. The association of predominantly ipsilateral blepharospasm and predominantly contralateral hemiparkinsonism is very rare, and its association with a posterior fossa space‐occupying lesion has been reported only once. This is the second report of such an association and the first description of adult‐onset symptomatology.</div>
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